Protein kinase A (PKA)

G_PKA

What does this word mean?

The downstream effector kinase of cAMP and the signalling cascade node from which multiple pathways branch.

Expanded note

PDRN activates PKA via cAMP, which then relays the signal and ultimately upregulates PI3K/Akt and VEGF expression.

A real example from our data

Not a generic example.

PMID 42351669 observed changes in the A2A, PKA and VEGF pathways together in a DSS-induced ulcerative colitis model.

Related terms

Where this term appears