Polynucleotide (PN)
G_PNWhat does this word mean?
A DNA polymer with longer fragments than PDRN that plays a dominant role in extracellular matrix remodelling and is the common abbreviation in injectable aesthetics.
Expanded note
PN and PDRN are structurally similar but functionally different. PN remodels the extracellular matrix while PDRN activates adenosine receptors and supports nucleotide synthesis, and the two also differ in molecular weight spectrum and regulatory route. PN should never be read as PDRN.
Not a generic example.
Korean Rejuran series products are commonly categorised as PN or Polynucleotide products.
Related terms
Where this term appears
Educational reference only. This site does not provide medical advice, treatment courses, injection counts, clinic recommendations or price recommendations.
PDRN is not approved by the FDA for injection or any therapeutic use. Topical and injectable PDRN are parallel facts under different regulatory pathways and must not be directly equated.
PN is not PDRN. Evidence grades are labelled on every factual element; in vitro and animal research is never described as clinical efficacy.